Flashcard Friends - Create flash cards, find and modify existing flash cards, share them with friends, test yourself...it's fun, free & it works!

List	Flip	Flash	Print

Categories > Science > Hematology

Deck Name: Hematology Images (50 cards)

You need flash player installed to be able to hear sounds on this page.

Fill in The Blanks
1.	(bcl-2 stain)	Answer:
2.		Answer:
3.		Answer:
4.	TRAP stain	Answer:
5.	Patient with DIC	Answer:
6.		Answer:
7.		Answer:
8.		Answer:
9.		Answer:
10.		Answer:
11.		Answer:
12.		Answer:
True or False Questions
13.	Response: Monocyte	True False
14.	Response: Band PMN	True False
15.	Response: EBV - infectious mononucleosis -- B-cells infected, but showing atypical/reactive T-cells; Downey cells	True False
16.	Response: Sideroblastic Anemia ("cut salami") - Ring sideroblasts signify MDS	True False
17.	Response: Burkitt Lymphoma t(8;14) -- vacuoles, starry night; associated with EBV	True False
18.	Lacunar cells Response: Mixed cellularity HL - mononuclear RS cells (infected w/ EBV)	True False
19.	left shift;15% or more metamyelocytes, myelocytes, and even promyelocytes is present. Basophils are increased. Response: APML - acute promyelocytic leukemia t(15;17) -- Tx= ATRA (all-trans retinoic acid)	True False
20.	Response: Sickle cell anemia -- in kids, RBCs get sequestered in spleen, splenomegaly, autoinfarction, then spleen shrinks as they go into adulthood; risk of aplastic crisis if Folate deficiency or infected with Parvo B19; Tx by hydroxyurea	True False
21.	M-spike; Bence-Jones proteins; lytic bone lesions; BM biopsy shows sheet of plasma cells -> plasmacytosis; Response: Multiple myeloma - Plasma cell dyscrasia	True False
22.	Response: Sicke cell anemia	True False
23.	Response: Spherocytes - hereditary spherocytosis; or warm autoimmune hemolytic anemia; splenomegaly; risk of aplastic crisis if infected with Parvo B19	True False
24.	Response: Megaloblastic anemia - due to B12 deficiency, folate deficiency, myelodysplasia, or anything that inhibits DNA synthesis (chemotherapy, etc)	True False
Matching Answers
(Please enter the letter of the correct answer)
25.	Hairy cell leukemia - B-cell leukemia; generally good prognosis (Tx by Cladrabine) TRAP test; * NO LYMPHADENOPATHY;	A.
26.	Mixed cellularity HL - mononuclear RS cells (infected w/ EBV)	B.
27.	Reed-Sternberg cell (owl eyes) - marker for Hodgkin's Lymphoma -- CD15+; CD30+ ; CD45- ; nodular sclerosing HL is most common subtype	C.
28.	unilobate megakaryocytes in MDS	D.
29.	Megaloblastic Anemia - impaired DNA synth due to B12 or Folate deficiency	E.
30.	Pelger-Heuetoid cell - characteristic of MDS	F.
31.	Rouleux - forming in patient with Multiple myeloma (clonal proliferation of plasma cells); hypercalcemia; lytic bone lesions; M-spike (due to homogeneous Ig production); Bence-Jones proteins (toxic to renal tubules); Tx by autologus BMT, thalidomide, bort	G.
32.	Megaloblastic anemia - due to B12 deficiency, folate deficiency, myelodysplasia, or anything that inhibits DNA synthesis (chemotherapy, etc)	H.
33.	Downey Cell - Atypical lymphocyte associated with infectious mononucleosis (EBV infection)	I.
34.	PMN	J.
35.	CLL - lymphoid cells in CLL are slightly larger than normal	K.
36.	Bite cell - splenic phagocytes bite out clump of Heinz bodies (oxidized/denatured Hb) that form as a result of G6PD deficiency	L. Atypical megakaryocytes
Multiple Choice Questions
37.		A. Essential Thrombocytosis (ET) - mutant JAK2; ^ platelets but dysfunctional, so ->bleeding ; ^ megakaryocytes; diagnosis by exclusion.. B. Elliptocytes - indicative of thalassemia or Fe/Folate deficiency C. AML M3 == APML; t(15;17); risk of DIC is high D. Elliptocytes - indicative of thalassemia or Fe/Folate deficiency
38.		A. AML M3 == APML; t(15;17); risk of DIC is high B. Plasma cells C. Plasma cells D. Bite cell - splenic phagocytes bite out clump of Heinz bodies (oxidized/denatured Hb) that form as a result of G6PD deficiency
39.		A. Peautrier Microabscesses - T-cells aggregate in the skin -- T-cell lymphoma (Just memorize for the Boards) B. Aplastic anemia C. Peautrier Microabscesses - T-cells aggregate in the skin -- T-cell lymphoma (Just memorize for the Boards) D. AML M3 == APML; t(15;17); risk of DIC is high
40.		A. Normal RBC B. Normal RBC C. AML M3 == APML; t(15;17); risk of DIC is high D. Downey Cell - Atypical lymphocyte associated with infectious mononucleosis (EBV infection)
41.		A. Normal blood smear B. Normal blood smear C. AML M3 == APML; t(15;17); risk of DIC is high D. Hairy cell leukemia
42.		A. Nucleated RBC - note red/pink color of cytoplasm. This may look like plasma cell, but plasma cells rarely appear in PBS. B. Spherocytes - hereditary spherocytosis; or warm autoimmune hemolytic anemia; splenomegaly; risk of aplastic crisis if infected with Parvo B19 C. AML M3 == APML; t(15;17); risk of DIC is high D. Nucleated RBC - note red/pink color of cytoplasm. This may look like plasma cell, but plasma cells rarely appear in PBS.
43.		A. Sicke cell anemia B. Spherocytes - hereditary spherocytosis; or warm autoimmune hemolytic anemia; splenomegaly; risk of aplastic crisis if infected with Parvo B19 C. Spherocytes - hereditary spherocytosis; or warm autoimmune hemolytic anemia; splenomegaly; risk of aplastic crisis if infected with Parvo B19 D. AML M3 == APML; t(15;17); risk of DIC is high
44.	Meyloperoxidase staining:	A. AML M3 == APML; t(15;17); risk of DIC is high B. Lymphocytes C. Germinal center stains positive for BCL-2, so this is a malignant lymphoma D. Mixed cellularity HL - mononuclear RS cells (infected w/ EBV)
45.		A. Cytokeratin stain to visualize cancer metastatis to bone marrow B. Cytokeratin stain to visualize cancer metastatis to bone marrow C. Megaloblastic anemia - due to B12 deficiency, folate deficiency, myelodysplasia, or anything that inhibits DNA synthesis (chemotherapy, etc) D. Cytokeratin stain to visualize cancer metastatis to bone marrow
46.		A. Neutrophil Toxic granulation B. Nodular Sclerosing Hodgkin's Lymophoma C. Neutrophil Toxic granulation D. Neutrophil Toxic granulation
47.		A. Basophil B. Peautrier Microabscesses - T-cells aggregate in the skin -- T-cell lymphoma (Just memorize for the Boards) C. Basophil D. Basophil
48.		A. Eosinophils B. Basophil C. Eosinophils D. Eosinophils
49.		A. Auer Rod --> AML Acute Myelogenous Leukemia -- Acquired mutation arrests marrow stem cell maturation at various stages B. Auer Rod --> AML Acute Myelogenous Leukemia -- Acquired mutation arrests marrow stem cell maturation at various stages C. Auer Rod --> AML Acute Myelogenous Leukemia -- Acquired mutation arrests marrow stem cell maturation at various stages D. Basophil
50.		A. Rouleux - forming in patient with Multiple myeloma (clonal proliferation of plasma cells); hypercalcemia; lytic bone lesions; M-spike (due to homogeneous Ig production); Bence-Jones proteins (toxic to renal tubules); Tx by autologus BMT, thalidomide, bort B. Lymphocytes C. Lymphocytes D. Lymphocytes